(C) 2009 IBRO. Published by Elsevier Ltd. All rights reserved.”
“Purpose: We report outcomes from ureteroureterostomy
performed through an inguinal herniorrhaphy type incision for definitive management of ectopic ureters or ureteroceles in the absence of ipsilateral click here lower pole reflux.
Materials and Methods: Records were reviewed for 23 consecutive patients who underwent lower ureteroureterostomy for 26 duplicated systems with ectopic ureter or ureterocele and no ipsilateral lower pole reflux. In 21 patients surgery was performed through an inguinal incision similar to that for herniorrhaphy, while a Pfannenstiel incision was used initially in the series in 2 others with bilateral duplex systems. buy PLX4032 Median patient age at operation was 10 months (range 2 to 56).
Results: At a mean followup of 26 months preoperative upper pole hydronephrosis and distal upper ureteral dilatation had resolved or improved in all cases. Preliminary
cutaneous ureterostomy was performed on 4 ureters (3 patients), 2 because the recipient lower pole ureter was thought to be too small for incision and anastomosis, 1 because of purulent drainage and 1 following inadvertent transection of the lower pole ureter. Mean surgical time for inguinal ureteroureterostomy was 101 minutes and mean postoperative hospitalization was 0.6 days. Except for dextranomer/hyaluronic acid injection in 1 patient with symptomatic grade I ipsilateral lower pole reflux, no additional surgical procedures were performed after ureteroureterostomy.
Conclusions: Lower ureteroureterostomy offers potentially definitive treatment for ectopic ureter or ureterocele without ipsilateral lower pole reflux, and can be triclocarban performed through an inguinal
herniorrhaphy type incision.”
“It has been long known that the physiological concentrations of polyamines putrescine, spermidine and spermine are essential for cell growth. However, the role of endogenous polyamines in behavior function is poorly understood at present. This study investigated animals’ behavioral performance and neurochemical changes in the hippocampus and prefrontal cortex following i.c.v. microinfusion of difluoromethylornithine (DFMO), a potent inhibitor of putrescine synthesis. Rats with low (25 mu g) and high (50 mu g) doses of DFMO spent significantly less time on the open arms and more time on the enclosed arms in the elevated plus maze relative to the saline controls, with no performance changes in the open field. The two DFMO groups were not impaired in the place and cued navigation, reversal training and probe tests in the water maze task. In the object recognition memory task, all three groups could detect the novel object, but rats in the high dose DFMO group spent significantly less time exploring displaced objects relative to the controls.