Infrared spectroscopy was also used to characterize these modified surfaces. The ability of the grafted surfaces to allow adsorption of proteins selleck compound was evaluated as a function of temperature. The results showed
that the amount of proteins adsorbed on the polyurethane membranes could be radically changed by altering the temperature above or below 32 degrees C. In vivo biocompatibility tests were performed on P-N-IPPAm samples, and no indication of toxicity was noted after 7 days of implantation. (C) 2011 Wiley Periodicals, Inc. J Appl Polym Sci 121: 3501-3508, 2011″
“Purpose: To evaluate perfusion parameter changes in patients with glioblastoma multiforme by comparing the perfusion magnetic resonance (MR) imaging measurements obtained before combined radiation and temozolomide therapy (RT-TMZ) with the follow-up MR imaging measurements obtained 1 month after completion of this treatment.
Materials and Methods: Institutional review board approval was obtained, and HIPAA guidelines were followed. The data of 36 patients (24 male [median age, 63 years]; 12 female [median age, 59 years]) with glioblastoma multiforme who were treated with RT-TMZ were retrospectively reviewed. The hypothesis was that a change in relative cerebral blood volume (rCBV) 1 month after RT-TMZ is predictive of overall survival. Linear regression analysis was performed to correlate
changes in tumor size and perfusion parameters with overall survival. Receiver operating characteristic (ROC) curves were evaluated for 1-year survival. Overall survival was assessed P005091 research buy with Kaplan-Meir survival curves and log-rank testing.
Results: Percentage change in rCBV at 1 month after RT-TMZ correlated with overall survival. Increased rCBV after treatment this website was a strong predictor of poor survival (median survival, 235 days versus 529 days with decreased rCBV) (P < .008, log-rank test). The ROC curves for 1-year survival showed a greater area under the curve (0.806; 95% confidence interval [CI]: 0.698, 0.970) (P = .005) with rCBV than with tumor size (0.556; 95% CI: 0.342, 0.729) (P = .382).
The overall survival for patients with increased tumor size, based on Macdonald criteria, was shorter than that for patients who showed no progression (stable or partial response), but the difference was not significant (median survival, 442 days versus 598 days) (P = .761, log-rank test).
Conclusion: Change in rCBV after RT-TMZ appears to correlate with overall survival. (C) RSNA, 2010″
“This study proposes a new method to locate and measure the temperature of the hot spots caused by Joule Heating by measuring the free thermal expansion in-plane strain. It is demonstrated that the hotspot caused by the Joule heating in a thin metal film/plate structure can be measured by Phase shifting Moire interferometry with continuous wavelet transform (PSMI/CWT) at the microscopic scale.